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Quick-Clot powder could save lives in severe trauma bleeding

NCT ID NCT05449834

Recruiting now Disease control Sponsor: Australian and New Zealand Intensive Care Research Centre Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two treatments to help blood clot in severely injured trauma patients who are bleeding heavily. One is a standard frozen blood product (cryoprecipitate) that takes time to thaw, and the other is a dry powder (fibrinogen concentrate) that can be given at the bedside. The goal is to see if the faster option helps patients spend more days alive and out of the hospital within 90 days. About 850 adults from Australia and New Zealand will take part.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease injury Shock, Hemorrhagic vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COAGULOPATHY HAEMORRHAGIC SHOCK TRAUMA

Contacts and locations

Locations

  • Alfred Hospital

    RECRUITING

    Melbourne, Victoria, 3004, Australia

  • Aukland City Hospital

    NOT_YET_RECRUITING

    Auckland, Aukland, 1023, New Zealand

  • Cairns Hospital

    RECRUITING

    Cairns, Queensland, 4870, Australia

  • Flinders Medical Centre

    RECRUITING

    Adelaide, South Australia, 5042, Australia

  • Gold Coast University Hospital

    RECRUITING

    Gold Coast, Queensland, 4215, Australia

  • John Hunter Hospital

    RECRUITING

    Newcastle, New South Wales, 2305, Australia

  • Liverpool Hospital

    RECRUITING

    Sydney, New South Wales, 2170, Australia

  • Middlemore Hospital

    NOT_YET_RECRUITING

    Auckland, Aukland, 2025, New Zealand

  • Princess Alexandra Hospital

    RECRUITING

    Brisbane, Queensland, 4102, Australia

  • Rockhampton Hospital

    RECRUITING

    Rockhampton, Queensland, 4700, Australia

  • Royal Adelaide Hospital

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Royal Brisbane and Women's Hospital

    RECRUITING

    Brisbane, Queensland, 4006, Australia

  • Royal Darwin Hospital

    RECRUITING

    Darwin, Northern Territory, 0810, Australia

  • Royal Hobart Hospital

    RECRUITING

    Hobart, Tasmania, 7000, Australia

  • Royal Melbourne Hospital

    RECRUITING

    Melbourne, Victoria, 3050, Australia

  • Royal North Shore Hospital

    RECRUITING

    Sydney, New South Wales, 2065, Australia

  • Royal Perth Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

  • Royal Prince Alfred Hospital

    RECRUITING

    Sydney, New South Wales, 2050, Australia

  • St Vincent's Hospital

    RECRUITING

    Sydney, New South Wales, 2010, Australia

  • Sunshine Coast University Hospital

    RECRUITING

    Sunshine Coast, Queensland, 4575, Australia

  • Townsville Hospital

    RECRUITING

    Townsville, Queensland, 4814, Australia

  • Waikato Hospital

    RECRUITING

    Hamilton, Hamilton, 3204, New Zealand

  • Wellington Hospital

    RECRUITING

    Wellington, Wellington Region, 6021, New Zealand

  • Westmead Hospital

    RECRUITING

    Sydney, New South Wales, 2145, Australia

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