Poop pills? fecal transplants tested for liver disease

NCT ID NCT06478602

Completed Disease control Sponsor: Cristian Ichim Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 3 trial tested whether fecal microbiota transplantation (FMT) could help people with liver cirrhosis. Nineteen patients received FMT via colonoscopy. Researchers measured liver stiffness and signs of brain confusion (hepatic encephalopathy) one month later. The goal was to see if changing gut bacteria could ease cirrhosis complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fecal microbiota transplantation
What this could lead to: If it works, this could point toward a new way to manage liver cirrhosis by improving gut health.
What could go wrong: This is a very small completed trial with only 19 participants, so results may not apply to everyone. The approach is still experimental and carries risks like infection or complications from colonoscopy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis hepatic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIVER CIRRHOSIS

Contacts and locations

Locations

County Clinical Emergency Hospital of Sibiu

Sibiu, 550245, Romania

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