Can wearables unlock the link between fatigue and movement in lung cancer?
NCT ID NCT07799974
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
This observational study follows 50 adults with locally advanced or metastatic lung cancer who are starting chemotherapy or immunotherapy. Researchers want to see how cancer-related fatigue and daily physical activity change during treatment, and whether those changes are connected. Participants wear activity monitors and a smartwatch, answer daily smartphone questions, and complete questionnaires on fatigue, sleep, and quality of life over six study visits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If the study succeeds, it could point toward ways to predict or manage fatigue during lung cancer treatment, potentially improving quality of life.
- What could go wrong
- This is an observational study with 50 participants, so it cannot prove cause and effect. Results may not apply to all lung cancer patients, and the findings will need confirmation in larger studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will include patients with locally advanced irresectable or metastatic lung cancer, who are planned to undergo systemic treatment (chemotherapy and/or immunotherapy).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Locally advanced irresectable or metastatic lung cancer (all histologies including NSCLC and SCLC). * ≥18 years. * ECOG performance status of ≤2 (a lower score indicates a higher performance status), assessed by the clinician (10). * Planned to start a first-line systemic treatment consisting of chemotherapy and/or immunotherapy. Patients who receive radiotherapy, concurrently or sequentially, within a multimodality treatment approach for locally advanced lung cancer are allowed. * Ability to give informed consent. Exclusion Criteria: * Being planned for primary radiotherapy with radical intent only or treatment with targeted therapies (mostly tyrosine kinase inhibitors (TKI's)). * Having complicated or unstable bone metastases (as judged by the clinician). * Unstable heart disease, including unstable congestive heart failure, arrythmia, or myocardial infarction diagnosed within the last 3 months. * Other malignancies in the last 2 years (except for adequately treated basal cell, superficial or in situ cancer of the bladder or the cervix). * Have musculoskeletal problems precluding them to be physically active. * Not understanding and speaking Dutch.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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