New immune drug takes on Hard-to-Treat cancers

NCT ID NCT07583316

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new drug called CRPA1A2, which helps the body's immune cells attack cancer cells. It is for people with certain advanced solid tumors (like lung, esophagus, head and neck, or liver cancer) that have not responded to other treatments. The study will first find a safe dose, then test that dose in more patients to see if it shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CRPA1A2 (a bispecific T cell engager)

What this could lead to

If successful, this could point toward a new treatment option for certain advanced solid tumors that have not responded to standard therapies.

What could go wrong

This is an early Phase 1 trial, so the main goal is safety, not effectiveness. It is very small and may not work in larger groups. Side effects from T cell engagers can be severe.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms esophageal squamous cell carcinoma head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma hepatocellular carcinoma lung cancer lung neoplasm Neoplasm Metastasis squamous cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••