Could a 30-Year-Old blood vessel drug ease Parkinson's?

NCT ID NCT05931575

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This phase 2 trial tests whether fasudil, a drug already used in Japan for blood vessel spasms, is safe and can help symptoms in people with early Parkinson's disease. 75 participants will take either fasudil or a placebo for 3 weeks. The study focuses on safety and tolerability, with a look at symptom changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fasudil hydrochloride

What this could lead to

If successful, this could point toward a new treatment option to ease symptoms of early Parkinson's disease.

What could go wrong

This is a small, early-phase trial (75 people, 3 weeks) focused on safety and tolerability, not proof of effectiveness. The drug may not improve symptoms or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Technische Universität München, Klinikum rechts der Isar, Klinik und Poliklinik für Neurologie

    Munich, 81675, Germany