Could a 30-Year-Old blood vessel drug ease Parkinson's?

NCT ID NCT05931575

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This phase 2 trial tests whether fasudil, a drug already used in Japan for blood vessel spasms, is safe and can help symptoms in people with early Parkinson's disease. 75 participants will take either fasudil or a placebo for 3 weeks. The study focuses on safety and tolerability, with a look at symptom changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Fasudil hydrochloride
What this could lead to
If successful, this could point toward a new treatment option to ease symptoms of early Parkinson's disease.
What could go wrong
This is a small, early-phase trial (75 people, 3 weeks) focused on safety and tolerability, not proof of effectiveness. The drug may not improve symptoms or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Technische Universität München, Klinikum rechts der Isar, Klinik und Poliklinik für Neurologie

    Munich, 81675, Germany

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