New radioactive dye could sharpen heart scans
NCT ID NCT04528758
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This early study tests a new radioactive dye, F-18 rhodamine 6G, to see if it can produce clearer PET scans of the heart. The dye is injected and then images are taken to measure blood flow in the heart muscle. The trial includes both healthy volunteers and people with stable coronary artery disease. The goal is to evaluate image quality and whether the dye can accurately show blood flow in small and large heart vessels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a radioactive form of rhodamine 6G called F-18 rhodamine 6G, used as a PET imaging dye
- What this could lead to
- If successful, this imaging method could provide clearer, more detailed heart scans to help doctors assess coronary artery disease and blood flow in both small and large heart vessels.
- What could go wrong
- This is a very early, small study (15 people) focused on image quality and safety, not on treating disease. The dye may not prove better than existing methods, and its use is limited to imaging, not therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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