Eye-tracking test may predict which gamers benefit from naltrexone

NCT ID NCT04649892

Recruiting now Symptom relief Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether eye-tracking patterns can predict how well naltrexone reduces symptoms of videogame disorder. Forty adults with the condition receive naltrexone and placebo in a crossover design, with eye-tracking assessments before and after each dose. The goal is to see if a simple eye test could guide personalized treatment for gaming addiction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: naltrexone, an opioid receptor blocker taken orally
What this could lead to: If eye tracking can predict who responds to naltrexone, it could point toward a personalized treatment for gaming disorder.
What could go wrong: This is a small, early-phase trial with only 40 participants. Naltrexone may not reduce gaming symptoms, and eye-tracking predictions may not prove reliable.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GAMING DISORDER

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Hospital das Clínicas da faculdade de medicina da Universidade de São Paulo
RECRUITING

São Paulo, São Paulo, 05403-000, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••

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