Spinal drain may ease brain pressure after severe head trauma
NCT ID NCT05889650
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether draining fluid from the spine (external lumbar drainage) is safe and doable for people with severe traumatic brain injury who have high pressure inside the skull. Thirty adults aged 18-65 will receive either standard care alone or standard care plus the spinal drain. The main goal is to see if the procedure increases the risk of brain herniation or death.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
External lumbar drainage (a procedure to drain fluid from the spine)
What this could lead to
If successful, this could provide a new way to safely lower brain pressure in severe head injury patients, potentially reducing complications.
What could go wrong
This is a very early, small safety trial with only 30 participants. The procedure carries risks like brain herniation or neurological worsening, and it may not prove effective.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brooke Army Medical Center
RECRUITINGFort Sam Houston, Texas, 78234, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Kansas University Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact Email: •••••@•••••
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University of Florida
RECRUITINGGainesville, Florida, 32610, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University of Houston Medical Center
RECRUITINGHouston, Texas, 77030, United States
Contact
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University of Texas
RECRUITINGSan Antonio, Texas, 78249, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••