Custom skull cap may stop brain sinking after Life-Saving surgery

NCT ID NCT06899711

First seen May 11, 2026

Summary

This study tests whether a custom 3D-printed external skull cap can prevent Sunken Flap Syndrome, a condition where the brain sinks after part of the skull is removed. 72 patients who had decompressive craniectomy will either wear the cap or not, and researchers will compare brain function and recovery. The goal is to see if the cap protects the brain and reduces the need for extra medical care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins Bayview Medical Center

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

External cranial prosthesis (3D-printed external skull plate)

What this could lead to

If it works, this could prevent Sunken Flap Syndrome after skull-removal surgery, reducing brain function decline and healthcare costs.

What could go wrong

This is a small, early-stage study with only 72 participants. The device may cause discomfort or not prevent the syndrome, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic ischemic stroke traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.