ALS patients get expanded access to experimental Sugar-Based drug
NCT ID NCT05597436
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This program gives ALS patients who cannot join other clinical trials access to an experimental drug called trehalose (SLS-005). Trehalose is a sugar solution given once a week through a vein. The goal is to see if it can help control the disease. The program is no longer available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
trehalose (SLS-005)
What this could lead to
If this works, it could slow progression of ALS and improve quality of life for patients who cannot join other trials.
What could go wrong
This is an expanded access program, not a formal trial, so evidence is limited. Trehalose is still investigational and may not slow the disease or may cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Barrow Neurological Institute
Phoenix, Arizona, 85013, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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George Washington University
Washington D.C., District of Columbia, 20052, United States
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Holy Cross Hospital - Phil Smith Neuroscience Institute
Fort Lauderdale, Florida, 33308, United States
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Hospital for Special Care
New Britain, Connecticut, 06053, United States
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Lehigh Valley Hospital
Allentown, Pennsylvania, 18105, United States
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Nova Southeastern University
Fort Lauderdale, Florida, 33328, United States
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SUNY Upstate Medical University
Syracuse, New York, 13210, United States
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Saint Alphonsus Regional Medical Center
Boise, Idaho, 83706, United States
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Sean M. Healey & AMG Center for ALS Neurological Clinical Research Institute, Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Spectrum Health/Corewell Health
Grand Rapids, Michigan, 49503, United States
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Texas Neurology, P.A.-Neal Site:769
Dallas, Texas, 75206, United States
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Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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University of California, Irvine
Orange, California, 92697, United States
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University of California, San Francisco
San Francisco, California, 94115, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
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University of Maryland School of Medicine
Baltimore, Maryland, 21201, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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Virginia Commonwealth University Clinical Research Unit
Richmond, Virginia, 23298, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States