Can exercise fix tiny muscle blood vessels in COPD?

NCT ID NCT02040363

Completed Knowledge-focused Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how exercise training affects the growth and maturation of tiny blood vessels in the leg muscles of people with COPD. Researchers will compare healthy volunteers and COPD patients doing different exercise intensities for 5 to 10 weeks. The goal is to understand why COPD patients have trouble building new blood vessels with exercise, which may limit their ability to be active.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise training
What this could lead to: If successful, this could help design better exercise programs for COPD patients to improve muscle function and quality of life.
What could go wrong: This is a small, early-stage study with only 22 participants, so results may not apply to all COPD patients. It focuses on biological markers, not direct health outcomes.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD PERIPHERAL MUSCLE DYSFUNCTION

Contacts and locations

Locations

Department of clinical Physiology - University Hospital

Montpellier, 34295, France

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