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Can exercise tame atrial fibrillation? trial tests workouts on heart rhythm and fitness

NCT ID NCT04508478

NEW Symptom relief Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers at National Taiwan University Hospital are testing how different exercise programs affect people with atrial fibrillation. Participants take part in aerobic training, resistance training, or a control physical exercise program. The study measures heart rhythm over 14 days, cardiopulmonary fitness through exercise tests, and body composition using scans. The goal is to see whether structured exercise changes heart burden, muscle metabolism, or body makeup in this population.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
structured exercise training programs, including aerobic and resistance training
What this could lead to
If exercise training helps, it could offer people with atrial fibrillation a low-cost way to improve heart and lung fitness and daily function alongside standard care.
What could go wrong
This is a very small study of 8 people, so results may not apply broadly. Exercise can trigger irregular heart rhythms in some patients, and the trial excludes people with unstable heart conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

8 people

The number who actually took part.

Started

Nov 2021

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Paroxysmal or persistent atrial fibrillation 2. Daily activity below moderate intensity \< 300 minutes or high intensity \< 150 minutes per week. Exclusion Criteria: 1. Active infection. 2. Implant cardiac pacemaker. 3. Uncontrolled hypertension. 4. Cardiopulmonary contraindication to exercise training, such as decompensated heart failure, acute pulmonary edema, unstable angina, uncontrolled arrhythmia causing hemodynamic compromise, symptomatic severe aortic stenosis, suspected dissecting aortic aneurysm, severe pulmonary hypertension, acute myocarditis, endocarditis or pericarditis, uncontrolled asthma and SpO2 \< 90% at rest on room air. 5. Inability to follow verbal command or to walk on treadmill or use stationary bike.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation

Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, Taiwan

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