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Exercise may strengthen immunity in CLL and NHL patients, study suggests

NCT ID NCT05876923

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how short-term and long-term exercise affects the immune system in people with slow-growing blood cancers like chronic lymphocytic leukemia (CLL) and indolent non-Hodgkin lymphoma (NHL). Researchers at Mayo Clinic will have 70 participants undergo a 12-week exercise program and measure changes in immune cells and function. The goal is to see if exercise can help these patients fight infections and delay the need for treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Exercise intervention
What this could lead to
If successful, this study could show that regular exercise strengthens the immune system in CLL and indolent NHL patients, potentially delaying disease progression and reducing infection risk.
What could go wrong
This is an early-stage observational study with only 70 participants. It is not designed to prove that exercise directly improves survival or delays treatment, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia chronic lymphocytic leukemia/small lymphocytic lymphoma indolent B-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LYMPHOCYTIC LEUKEMIA/SMALL LYMPHOCYTIC LYMPHOMA INDOLENT NON-HODGKIN LYMPHOMA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Arizona

    RECRUITING

    Scottsdale, Arizona, 85259, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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