Experimental cancer vaccine combo shows promise in small trial

NCT ID NCT03789097

First seen May 23, 2026 ยท Last updated May 23, 2026

Summary

This early-phase trial tested a combination of four therapies to train the immune system to attack cancer. 17 adults with non-Hodgkin's lymphoma, metastatic breast cancer, or head and neck cancer received low-dose radiation, an immune cell booster (Flt3L), an immune activator (Poly-ICLC), and the immunotherapy pembrolizumab. The goal was to see if this 'in situ vaccine' approach was safe and could shrink tumors.

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Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

Conditions

Explore the condition pages connected to this study.