Pump iron, boost brain? creatine and training tested for menopause

NCT ID NCT07027800

Completed Symptom relief Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether high-intensity resistance training plus creatine supplements can improve muscle quality and thinking skills in perimenopausal women. Fifty-five healthy women aged 38-60 took part, with some getting creatine, some a placebo, and some no supplement. The goal is to find simple ways to ease common menopause-related changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Creatine monohydrate (dietary supplement)
What this could lead to: If it works, this could point toward a simple way to improve muscle strength and thinking skills during perimenopause.
What could go wrong: This is a small pilot study with only 55 women, so results may not apply to everyone. The supplement may cause digestive upset or not show clear benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIMENOPAUSE

Contacts and locations

Locations

Applied Physiology Laboratory

Chapel Hill, North Carolina, 27713, United States

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Other studies related to the condition(s) this trial covers.