Can a 12-Week exercise program boost brain and body health in older adults with diabetes?

NCT ID NCT07711834

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study investigates whether a 12-week program combining aerobic and resistance exercise can improve blood sugar control and cognitive function in adults aged 65-79 with type 2 diabetes and mild memory issues. Participants follow a supervised exercise routine that gradually increases in intensity. The study also explores whether a specific gene variant (PPARGC1A rs8192678) affects how much individuals benefit from the exercise.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a 12-week combined aerobic and resistance exercise program
What this could lead to
If successful, this could show that a tailored exercise program helps manage blood sugar and thinking skills in older adults with diabetes and memory decline, and that genetic differences may influence how much someone benefits.
What could go wrong
This is a small, single-arm study with no control group, so results may not be generalizable. The exercise program is supervised and may not be feasible for all older adults outside a research setting.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Harbin Sport University

    Harbin, Heilongjiang, China

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