Exercise after surgery may keep metastatic colorectal cancer at bay

NCT ID NCT05579340

Ongoing Disease control Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a 6-month exercise program (a mix of aerobic and resistance training) can improve fitness and reduce the risk of cancer coming back in patients who had surgery for colorectal cancer that spread to the liver. About 66 participants will be split into three groups: standard care, standard care plus 150 minutes of exercise per week, or standard care plus 300 minutes per week. They will be followed for up to 3 years to track tumor recurrence and survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise training (aerobic and resistance)
What this could lead to: If it works, this could show that structured exercise after surgery helps improve fitness and may lower the chance of cancer returning.
What could go wrong: This is a small, early-phase trial with only 66 participants. Exercise may not affect cancer recurrence, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER COLORECTAL CANCER METASTATIC TO LIVER

Contacts and locations

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Locations

Rigshospitalet (CFAS)

Copenhagen, 2100, Denmark

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