New heart valve procedure tested to fix deadly leaks without major surgery

NCT ID NCT04221490

Summary

This study is testing a new device called the EVOQUE system, which is designed to replace a leaky tricuspid heart valve using a catheter inserted through a blood vessel, avoiding open-heart surgery. The trial aims to see if this procedure is safe and effective at reducing severe valve leakage and improving symptoms like shortness of breath and swelling in patients who are not well-managed with medication alone. It involves 228 participants at multiple medical centers.

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Contacts and locations

Locations

  • Baylor Heart Hopsital Plano

    Plano, Texas, 75093, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • CHU Bordeaux, Hôpital Cardiologique Haut Lévêque

    Pessac, 33600, France

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Clinique Pasteur

    Toulouse, 31076, France

  • Columbia University Irving Medical Center / NYPH

    New York, New York, 10032, United States

  • Emory University

    Atlanta, Georgia, 30308, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • InselSpital University Hospital Bern

    Bern, 3010, Switzerland

  • Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval (IUCPQ-ULaval)

    Québec, G1V 4G5, Canada

  • Massachusetts General Hospital Boston

    Boston, Massachusetts, 02114, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, 30309, United States

  • St. Michael's Hospital

    Toronto, Ontario, M5B 1W8, Canada

  • St. Paul's Hospital Vancouver

    Vancouver, British Columbia, V6Z1Y6, Canada

  • Stanford University

    Stanford, California, 94305, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.