New combo aims to tame breast cancer and blood sugar spikes

NCT ID NCT05455619

First seen Apr 25, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tests a new drug, evexomostat, added to two standard treatments for a common type of advanced breast cancer (HR+, HER2-). The goal is to see if the combination is safe and can reduce severe blood sugar spikes caused by the standard drugs. About 52 adults with specific genetic changes will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

  • Doctors Hospital of Laredo

    RECRUITING

    Laredo, Texas, 78045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hoag Memorial Hospital Presbyterian

    RECRUITING

    Newport, California, 92663, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hope and Healing Cancer Services

    RECRUITING

    Hinsdale, Illinois, 60521, United States

    Contact

  • Loma Linda University Cancer Center

    RECRUITING

    Loma Linda, California, 92354, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Miami Cancer Institute at Baptist Health

    RECRUITING

    Miami, Florida, 33176, United States

    Contact

    Contact Email: •••••@•••••

  • Penn State Milton S Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • SHARP Healthcare

    RECRUITING

    San Diego, California, 92123, United States

    Contact

  • Trinity Health

    RECRUITING

    Ypsilanti, Michigan, 48197, United States

    Contact

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.