New hope for kids with brain tumors: drug shows promise in slowing disease

NCT ID NCT01734512

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tested the drug everolimus in 65 children whose low-grade gliomas (slow-growing brain tumors) had come back or gotten worse. The goal was to see if the drug could stop the tumors from growing for at least 6 months. Children took everolimus by mouth and had regular MRI scans to check their tumors. The study aimed to find a new treatment option for these children when standard therapies stop working.

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Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital Oakland

    Oakland, California, 94609, United States

  • Children's Hospitals and Clinics of Minneapolis

    Minneapolis, Minnesota, 55404, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • St. Louis Children's Hospital, Washington University

    St Louis, Missouri, 63130, United States

  • The Children's Hospital Of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • University of California, Los Angeles

    Los Angeles, California, 90027, United States

  • University of California, San Diego Rady Children's Hospital

    San Diego, California, 92123, United States

  • University of California, San Francisco

    San Francisco, California, 94158, United States

  • University of Florida

    Gainesville, Florida, 32611, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

  • University of Washington, Seattle

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.