New heat treatment may cut cancer pain without extra drugs
NCT ID NCT05535894
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a procedure called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) to treat pain in 19 people with advanced pancreatic cancer that could not be removed by surgery. The goal was to see if zapping the celiac ganglion—a bundle of nerves—could reduce pain and improve quality of life. Researchers measured pain levels, medication use, and well-being before and after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiofrequency ablation of the celiac ganglion
What this could lead to
If it works, this could offer a new way to manage severe pain and reduce the need for strong painkillers in people with advanced pancreatic cancer.
What could go wrong
This was a small, early study with only 19 participants, so results may not apply to everyone. The procedure carries risks like bleeding or infection, and pain relief may not last long.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shailendra Singh
Morgantown, West Virginia, 26508, United States