New heat therapy for pancreatic lesions tested in 100-Patient registry

NCT ID NCT07136324

Ongoing Disease control Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks 100 people with pancreatic cysts or tumors who receive a treatment called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA). A thin needle delivers heat directly to the lesion to destroy it. Researchers will monitor how well the procedure works and any side effects over 7 years. The goal is to see if this minimally invasive approach can be a safe alternative to surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiofrequency ablation (RFA) delivered via an endoscopic ultrasound-guided catheter
What this could lead to: If successful, this could show that EUS-guided RFA is a safe and effective way to treat pancreatic cysts and tumors without major surgery.
What could go wrong: This is an early-stage registry, not a controlled trial, so results may not prove effectiveness. There are also standard risks like bleeding, infection, or damage to nearby organs.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm Pancreatic Cyst pancreatic neoplasm precancerous condition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CYST

Contacts and locations

Locations

Memorial Hermann Hospital

Houston, Texas, 77054, United States

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