Shock waves vs. scope: a Head-to-Head battle for kidney stone relief
NCT ID NCT07772635
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This trial compares two common procedures for treating upper ureteric stones: extracorporeal shock wave lithotripsy (ESWL), which uses external shock waves to break the stone, and semirigid ureteroscopy, where a thin scope is passed through the urinary tract to fragment the stone. Adults aged 18–75 with a single stone smaller than 10 mm are randomly assigned to one of the two treatments. The main goal is to see which approach achieves complete stone clearance, as confirmed by a CT scan four weeks later, while also tracking pain relief, number of sessions needed, and complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Extracorporeal shock wave lithotripsy (ESWL) or semirigid ureteroscopy
- What this could lead to
- If one procedure proves clearly better, it could become the preferred first-line treatment for small upper ureteric stones, improving success rates and reducing repeat procedures.
- What could go wrong
- This is a single trial with 100 participants, so results may not apply to everyone. Both procedures carry risks like pain, bleeding, or incomplete stone clearance, and the comparison may show no meaningful difference.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
100 people
The number who actually took part.
- Started
-
Dec 2025
- Finished
-
Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female participant aged 18 to 75 years Single unilateral upper ureteric stone located above the sacroiliac joint Stone confirmed by non-contrast computed tomography of the kidneys, ureters and bladder Stone maximum diameter less than 10 mm Stone density of 1000 Hounsfield units or less Written informed consent provided Willing and able to complete the assigned treatment and four-week follow-up Exclusion Criteria: * Solitary functioning kidney Bilateral ureteric stones Active urinary tract infection Deranged renal function Stone maximum diameter of 10 mm or greater Stone density greater than 1000 Hounsfield units Unable or unwilling to complete the assigned treatment or four-week follow-up
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Ureteral calculi are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sheikh Zayed Hospital
Lahore, 54810, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- World's largest kidney stone surgery study launches
- Can an amino acid help pass kidney stones better than a standard drug?
- Bladder drug may save kids from second surgery for kidney stones
- New stent aims to make kidney stone recovery less painful
- Sleep aid and bladder drug tested to ease stent discomfort
- Could a bladder rinse make emergency kidney stone treatment easier?