Scientists hunt for genetic clues to esophageal cancer in large study

NCT ID NCT00341276

Completed Knowledge-focused Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 30, 2026 · Updated 9 times

Summary

This completed study looked at genetic factors that might increase the risk of esophageal and stomach cancers. Researchers collected DNA samples from over 7,700 people, including patients with cancer and healthy individuals from high- and low-risk areas in China. The goal was to find genes linked to cancer susceptibility, which could help identify high-risk people for prevention or early detection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward genetic screening to identify people at high risk for esophageal cancer, enabling earlier prevention or detection.
What could go wrong: This is an observational genetics study, not a treatment trial. It may not directly lead to new therapies, and findings may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms gastric body carcinoma gastric cancer gastric cardia carcinoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESOPHAGEAL CANCER GASTRIC (CARDIA, BODY) CANCER

Contacts and locations

Locations

Shanxi Tumor Hospital and Institute

Taiyuan, China
Yangcheng County Cancer Hospital and Institute

Yangcheng, China

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