Can a common pain drug prevent post-surgery confusion in seniors?

NCT ID NCT07523334

First seen Apr 14, 2026 · Last updated Apr 29, 2026 · Updated 3 times

Summary

This study looks at whether esketamine, a drug often used for pain during surgery, can help prevent confusion and memory problems in older patients (65-90 years) after major non-cardiac surgery. About 120 participants will receive one of three different doses of esketamine to find the safest and most effective dose. The goal is to improve recovery without causing unwanted side effects like dissociation.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

    Contact Email: •••••@•••••

  • Tianjin Medical University General Hospital

    Tanjing, Tianjing, 300052, China

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.