New drug ER-100 tested for eye nerve damage: first human trial begins

NCT ID NCT07290244

First seen Jan 09, 2026 · Last updated May 08, 2026 · Updated 28 times

Summary

This early-phase study tests whether a single dose of ER-100 is safe for people with two eye nerve conditions: open-angle glaucoma and NAION. About 18 adults will receive the drug and be monitored closely for side effects, eye health, and vision changes over up to 5 years. The goal is to find out if ER-100 is safe enough to study further.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charleston Neuroscience Institute

    RECRUITING

    Charleston, South Carolina, 29414, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University Irving Medical Center/Edward S. Harkness Eye Institute

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Global Research Management, Inc.

    RECRUITING

    Glendale, California, 91204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mass Eye and Ear

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.