Heart attack drug targets tiny vessels, not blockages
NCT ID NCT05198791
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether eplerenone, a drug used for high blood pressure and heart failure, can help people who have had a heart attack or heart injury but no blocked arteries. Many of these patients have damage to tiny blood vessels in the heart. The study will involve 400 adults in Scotland. Participants with small vessel problems will either get eplerenone or usual care for six months. The main goal is to see if the drug reduces heart injury markers and improves heart function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Eplerenone (a tablet that reduces blood vessel injury, used for high blood pressure and heart failure)
What this could lead to
If it works, this could point toward a treatment for heart damage caused by small vessel problems after a heart attack.
What could go wrong
This is an early phase 2 trial with only 400 participants, so results may not apply to everyone. The drug may not reduce heart injury or improve outcomes as hoped.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Golden Jubilee National Hospital
RECRUITINGGlasgow, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
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University Hospital Hairmyres
RECRUITINGEast Kilbride, Lanarkshire, G75 8RG, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••