New RNA test could spot brain tumors without surgery

NCT ID NCT06575452

Recruiting now Diagnosis Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether chemical marks on RNA molecules found in blood and urine can help diagnose gliomas, a type of brain tumor. Researchers will collect samples from 228 adults scheduled for brain surgery and compare them to healthy controls. The goal is to develop a non-invasive test that could improve diagnosis and monitor tumor changes without relying solely on MRI scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood or urine test to diagnose gliomas and track their progression without repeated MRIs.
What could go wrong: This is an early-stage diagnostic study, not a treatment trial. The RNA markers may not prove accurate enough for clinical use, and results may not apply to all glioma types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

astrocytoma, IDH-mutant, grade 2 glioma IDH-mutant anaplastic astrocytoma IDH-wildtype glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA

Contacts and locations

Locations

CHU Montpellier - Hôpital St Eloi
RECRUITING

Montpellier, 34090, France
Insitut Régional du Cancer de Montpellier
RECRUITING

Montpellier, Hérault, 34298, France

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