New RNA test could spot brain tumors without surgery

NCT ID NCT06575452

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether chemical marks on RNA molecules found in blood and urine can help diagnose gliomas, a type of brain tumor. Researchers will collect samples from 228 adults scheduled for brain surgery and compare them to healthy controls. The goal is to develop a non-invasive test that could improve diagnosis and monitor tumor changes without relying solely on MRI scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood or urine test to diagnose gliomas and track their progression without repeated MRIs.

What could go wrong

This is an early-stage diagnostic study, not a treatment trial. The RNA markers may not prove accurate enough for clinical use, and results may not apply to all glioma types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

astrocytoma, IDH-mutant, grade 2 glioma IDH-mutant anaplastic astrocytoma IDH-wildtype glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Montpellier - Hôpital St Eloi

    RECRUITING

    Montpellier, 34090, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Insitut Régional du Cancer de Montpellier

    RECRUITING

    Montpellier, Hérault, 34298, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact