Nighttime seizures and dreams: new study probes the link

NCT ID NCT07605858

Recruiting now Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how epileptic brain activity during sleep can cause awakenings and change dream recall or content. Researchers will use tiny electrical pulses in the brain during sleep to trigger mild epileptic activity and observe the effects. The goal is to better understand the connection between epilepsy, sleep disruption, and dreaming in 20 adults with drug-resistant focal epilepsy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Direct electrical stimulation (DES) during sleep
What this could lead to: If successful, this could help doctors understand how nighttime seizures disrupt sleep and dreams, potentially guiding treatments to improve sleep quality in epilepsy patients.
What could go wrong: This is a small, early-stage study with only 20 participants, so results may not apply to everyone. It is designed to gather knowledge, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

epilepsy focal epilepsy frontal lobe epilepsy temporal lobe epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PATIENTS WITH DRUG-RESISTANT FOCAL EPILEPSY SEEG AS PART OF PRESURGICAL EVALUATION

Contacts and locations

Locations

Epilepsy Department, Duke University Hospital
NOT_YET_RECRUITING

Durham, North Carolina, 27710, United States
Service de Neurologie Fonctionnelle et d'Epileptologie Hôpital Neurologique, GHE, Hospices Civils de Lyon Hôpital Neurologique Pierre WERTHEIMER
RECRUITING

Bron, 69500, France

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