Study seeks optimal ephedrine dose for Infants' low blood pressure during surgery
NCT ID NCT02384876
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested different doses of the drug ephedrine to find the most effective one for treating low blood pressure that occurs during surgery in newborns and infants up to 6 months old. The trial involved 120 infants who developed low blood pressure while under anesthesia. Researchers compared several higher doses against a standard low dose to see which worked best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ephedrine
What this could lead to
If successful, this could establish a safer, more effective dose of ephedrine for treating low blood pressure during surgery in very young infants.
What could go wrong
This is a small, early-phase study (Phase 2) with only 120 participants, so results may not apply to all infants. The study is also completed, so no new data is being collected.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospices Civils de Lyon
Lyon, France
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Hôpital Nord
Saint-Etienne, 42055, France
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Hôpital d'Estaing
Clermont-Ferrand, 63003, France