Experimental cancer drug trial halted early

NCT ID NCT05980416

First seen Nov 14, 2025 · Last updated May 08, 2026 · Updated 22 times

Summary

This early-stage trial tested a new drug called EO-3021 in adults with advanced solid tumors, especially stomach cancer, that have a specific marker (CLDN18.2). The study aimed to find safe doses and check for side effects, but it was terminated early. About 88 people were expected to join.

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Contacts and locations

Locations

  • Atrium Health/Wake Forest University

    Charlotte, North Carolina, 28204, United States

  • City of Hope

    Duarte, California, 91010, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Henry Ford Cancer

    Detroit, Michigan, 48202, United States

  • Johns Hopkins University - Sibley Memorial Hospital

    Washington D.C., District of Columbia, 20016, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mary Crowley Cancer Research

    Dallas, Texas, 75230, United States

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cancer Center Hospital

    Chuo Ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • START Midwest

    Grand Rapids, Michigan, 49546, United States

  • Samsung Medical Center

    Seoul, South Korea

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute at Florida Cancer Specialists

    Orlando, Florida, 32827, United States

  • UW Carbone Cancer Center - Cancer Connect

    Madison, Wisconsin, 53792, United States

  • Yale - Smilow Cancer Hospital

    New Haven, Connecticut, 06519, United States

  • Yonsei University

    Seoul, South Korea

Conditions

Explore the condition pages connected to this study.