New drug targets joylessness in depression
NCT ID NCT07253324
First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 21 times
Summary
This early study tested an experimental drug called ENX-104 in 48 adults with major depressive disorder who also experience anhedonia (loss of interest or pleasure). The main goal was to check the drug's safety and how the body processes it. Researchers measured side effects and drug levels in the blood. This is a phase 1 trial, so it's one of the first steps in seeing if the drug might help ease symptoms.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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MAC Clinical Research
Blackpool, Lancashire, FY2 0JH, United Kingdom
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MAC Clinical Research
Prescot, Merseyside, L341BH, United Kingdom
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MAC Clinical Research
Cannock, South Staffordshire, WS11 0BN, United Kingdom
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MAC Clinical Research
Manchester, M13 9NQ, United Kingdom
Conditions
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