New combo inhaler aims to improve breathing in COPD patients
NCT ID NCT07016412
First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 3 times
Summary
This study tests a new fixed-dose combination of two drugs (ensifentrine and glycopyrrolate) given via nebulizer twice daily for 28 days in 480 adults with COPD. The goal is to see if the combination improves lung function more than either drug alone or placebo. The trial is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ensifentrine and glycopyrrolate combination
- What this could lead to
- If successful, this could lead to a new treatment option that helps people with COPD breathe better.
- What could go wrong
- This is an early Phase 2b trial with only 480 participants over 28 days. The combination may not work better than existing treatments, and side effects are still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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ASHA Clinical Research - Hammond
Hammond, Indiana, 46324, United States
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Advance Clinical Research
Kettering, Ohio, 45439, United States
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American Health Research Inc
Charlotte, North Carolina, 28277, United States
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Bernstein Clinical Research Center Inc
Cincinnati, Ohio, 45231-4927, United States
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California Medical Research Associates, Inc.
Northridge, California, 91324-6200, United States
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Carolina Research Center, Inc
Shelby, North Carolina, 28150-3803, United States
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Centricity Research Columbus Georgia Multispecialty - PPDS
Columbus, Georgia, 31904, United States
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Chattanooga Research & Medicine, PLLC
Chattanooga, Tennessee, 37404, United States
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ClinSearch - Chattanooga
Chattanooga, Tennessee, 37421, United States
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Clinical Research Associates of Central PA
DuBois, Pennsylvania, 15801-2277, United States
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Clinical Research Institute, Inc - CRN
Plymouth, Minnesota, 55441-2676, United States
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Clinical Research of Gastonia
Gastonia, North Carolina, 28054-7481, United States
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Clinical Research of Rock Hill
Rock Hill, South Carolina, 29732, United States
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Clinical Research of West Florida Inc
Clearwater, Florida, 33765, United States
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Clinical Research of West Florida Inc - Tampa
Tampa, Florida, 33606, United States
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Clinical Trials Center of Middle Tennessee
Franklin, Tennessee, 37067-5665, United States
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Corsicana Medical Research
Corsicana, Texas, 75110-2471, United States
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Downtown LA Research Center Inc - ClinEdge
Los Angeles, California, 90017, United States
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Element Research Group
San Antonio, Texas, 78258, United States
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Elite Clinical Studies, LLC
Phoenix, Arizona, 85018, United States
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Fleming Island Center For Clinical Research
Fleming Island, Florida, 32003, United States
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Florida Institute For Clinical Research LLC
Orlando, Florida, 32825-4454, United States
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Greater Heights Memorial Pulmonary and Sleep
Houston, Texas, 77008, United States
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Horizon CR: Houston Pulmonary Sleep & Allergy Associates - Cypress - ClinEdge - PPDS
Cypress, Texas, 77429, United States
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Horizon Family Medical Group - New Windsor Primary Care
New Windsor, New York, 12553-7754, United States
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Houston Pulmonary Medicine Associates, PA - Biopharma Informatic - PPDS
Houston, Texas, 77089, United States
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Huntsville Research Institute LLC
Huntsville, Texas, 77340, United States
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Inquest Clinical Research
Baytown, Texas, 77521, United States
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Lowcountry Lung and Critical Care PA
North Charleston, South Carolina, 29406, United States
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Midwest Chest Consultants PC
Saint Charles, Missouri, 63301, United States
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Midwest Clinical Research LLC
St Louis, Missouri, 63141-7051, United States
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Monroe Biomedical Research -343 Venus St
Monroe, North Carolina, 28112-4025, United States
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Monroe Biomedical Research Charleston
North Charleston, South Carolina, 29406, United States
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MultiSpecialty Clinical Research, Inc
Johnson City, Tennessee, 37604, United States
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Northern California Research Corp
Sacramento, California, 95821-2640, United States
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Ormond Beach Clinical Research
Ormond Beach, Florida, 32174-8196, United States
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Pharmacorp Clinical Trials Incorporated
Charleston, South Carolina, 29412, United States
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Piedmont Research Partners LLC
Fort Mill, South Carolina, 29707-4514, United States
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Progressive Medical Research
Port Orange, Florida, 32127-5169, United States
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Remington Davis Clinical Research
Columbus, Ohio, 43215, United States
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Revive Research Institute, Inc
Southfield, Michigan, 48075, United States
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SEC Clinical Research, LLC
Dothan, Alabama, 36305-7375, United States
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Sherman Clinical Research - 403 N. Highland Ave
Sherman, Texas, 75092, United States
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Sierra Clinical Research
Las Vegas, Nevada, 89106, United States
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Spartanburg Medical Research
Spartanburg, South Carolina, 29303-4755, United States
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Stern Research Partners, LLC
Huntersville, North Carolina, 28078, United States
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The Clinical Research Center LLC - CRN
St Louis, Missouri, 63141, United States
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Tranquil Clinical Research
Webster, Texas, 77598-4085, United States
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Trialfinity Clinical Research Center
Hamilton, New Jersey, 08619, United States
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Tucson Clinical Research Institute
Tucson, Arizona, 85712, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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Velocity Clinical Research
Spartanburg, South Carolina, 29303, United States
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Velocity Clinical Research (Rockville - Maryland) - PPDS
Rockville, Maryland, 20854-2960, United States
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Velocity Clinical Research - Anderson - PPDS
Anderson, South Carolina, 29621-4822, United States
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Velocity Clinical Research - Gaffney - PPDS
Gaffney, South Carolina, 29340-4737, United States
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Velocity Clinical Research - Union - PPDS
Union, South Carolina, 29379, United States
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Velocity Clinical Research - Valparaiso
Valparaiso, Indiana, 46383, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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