Bubble blast: new device aims to shatter kidney stones without surgery
NCT ID NCT06942949
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new device called the Enhanced Lithotripsy System (ELS) that uses low-pressure ultrasound to activate tiny bubbles in the urine, breaking kidney or ureter stones into small pieces that can pass naturally. The trial will enroll 101 adults with a single stone in the ureter. Participants receive the ELS procedure and are checked with a CT scan 30 days later to see if the stone is gone or reduced to fragments small enough to pass.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Enhanced Lithotripsy System (ELS) device with microbubbles
What this could lead to
If it works, this could offer a less painful way to break up urinary stones so they pass naturally, reducing the need for surgery.
What could go wrong
This is a small, early-stage trial with only 101 people. The device may not break stones effectively for everyone, and some may still need additional procedures.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Arizona State Urological Research Institute
RECRUITINGPhoenix, Arizona, 85225, United States
Contact Phone: •••-•••-••••
Contact
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Arkansas Urology Research Center
ENROLLING_BY_INVITATIONLittle Rock, Arkansas, 72211, United States
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Comprehensive Urologic Care
RECRUITINGLake Barrington, Illinois, 60010, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke
ACTIVE_NOT_RECRUITINGDurham, North Carolina, 27710, United States
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Georgia Urology
RECRUITINGRoswell, Georgia, 300076, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Golden State Urology
RECRUITINGSacramento, California, 95823, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Michael G. Oefelein Clinical Trials
ACTIVE_NOT_RECRUITINGBakersfield, California, 93301, United States
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Minnesota Urology
RECRUITINGWoodbury, Minnesota, 55125, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nebraska Urology
ENROLLING_BY_INVITATIONLincoln, Nebraska, 68516, United States
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SUNY - Upstate Medical University
RECRUITINGSyracuse, New York, 13210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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San Diego Clinical Trials
RECRUITINGLa Mesa, California, 91942, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Miami Hospital
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Rochester Medical Center
RECRUITINGRochester, New York, 14620, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Virginia
WITHDRAWNCharlottesville, Virginia, 22903, United States
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University of Virginia Community Health
ACTIVE_NOT_RECRUITINGCulpeper, Virginia, 22701, United States
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Urology Nevada
ENROLLING_BY_INVITATIONReno, Nevada, 89511, United States
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Urology San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Urology Specialists Clinic
ENROLLING_BY_INVITATIONSioux City, South Dakota, 57108, United States
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Urology of Virginia
RECRUITINGVirginia Beach, Virginia, 23462, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wichita Urology Group
RECRUITINGWichita, Kansas, 67226, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact