Laser showdown: which device rejuvenates skin best?

NCT ID NCT03767972

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study aimed to compare several energy-based devices (like lasers and radiofrequency) for skin rejuvenation on the face, hands, and other areas. It enrolled 24 adults with signs of skin aging. The trial was terminated early, so the planned comparison of effectiveness and side effects was not completed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Energy-based devices (lasers and radiofrequency devices such as Fraxel Restore, Helios III, PicoWay, Halo, ThermiVa, DiVa)

What this could lead to

If successful, this could show which energy-based device works best for skin rejuvenation with fewer side effects.

What could go wrong

The trial was terminated early, so we have limited data. It is a small, early study comparing many devices, making it hard to draw firm conclusions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, Irvine, Dermatology Clinical Research Center

    Irvine, California, 92697, United States