Laser showdown: which device rejuvenates skin best?

NCT ID NCT03767972

Terminated Symptom relief Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study aimed to compare several energy-based devices (like lasers and radiofrequency) for skin rejuvenation on the face, hands, and other areas. It enrolled 24 adults with signs of skin aging. The trial was terminated early, so the planned comparison of effectiveness and side effects was not completed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Energy-based devices (lasers and radiofrequency devices such as Fraxel Restore, Helios III, PicoWay, Halo, ThermiVa, DiVa)
What this could lead to: If successful, this could show which energy-based device works best for skin rejuvenation with fewer side effects.
What could go wrong: The trial was terminated early, so we have limited data. It is a small, early study comparing many devices, making it hard to draw firm conclusions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

REJUVENATION

Contacts and locations

Locations

University of California, Irvine, Dermatology Clinical Research Center

Irvine, California, 92697, United States

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