New drug targets gene mutation to boost blood counts in rare blood disorder

NCT ID NCT06240754

First seen Feb 13, 2026 · Last updated May 09, 2026 · Updated 12 times

Summary

This study tests whether enasidenib, a drug that blocks a faulty protein from a mutated IDH2 gene, can safely improve blood cell counts in people with clonal cytopenia of undetermined significance (CCUS). About 15 adults with unexplained low blood counts for at least 6 months and an IDH2 mutation will take part. The goal is to see if the drug can reduce symptoms and control the condition.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.