Experimental drug targets rare blood condition in tiny pilot study

NCT ID NCT05102370

Completed Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a drug called enasidenib in 4 people with a rare blood condition (CCUS) and a specific gene change (IDH2). The goal was to see if the drug could safely improve low blood cell counts. The study is complete, but results are not yet reported.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CCUS CLONAL CYTOPENIA OF UNDETERMINED SIGNIFICANCE CLONAL CYTOPENIA OF UNDETERMINED SIGNIFICANCE

Contacts and locations

Locations

Cleveland Clinic (Data Collection Only)

Cleveland, Ohio, 44195, United States
Mayo Clinic (Data Collection Only)

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Bergen (Limited protocol activities)

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (All protocol activities)

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited protocol activities)

Rockville Centre, New York, 11553, United States
Memorial Sloan Kettering Suffolk-Commack (Limited protocol activities)

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, New York, 10604, United States
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, 07920, United States
Ohio State University (Data Collection Only)

Columbus, Ohio, 43210, United States
Oregon Health & Science University (Data Collection Only)

Portland, Oregon, 97239, United States
Washington University (Data Collection and Specimen Analysis)

St Louis, Missouri, 63110, United States

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