IVF breakthrough? trial tests embryo 'Defrag' to boost pregnancy chances

NCT ID NCT07500337

Recruiting now Disease control Sponsor: Momo Fertilife Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether removing tiny cell fragments from day-4 embryos (a procedure called defragmentation) can help them develop into healthy blastocysts and lead to more pregnancies. About 320 women undergoing IVF will be randomly assigned to have their embryos defragmented or left alone. The goal is to see if this extra step improves usable blastocyst rates and live birth outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mechanical or laser-assisted embryo defragmentation
What this could lead to: If successful, this procedure could increase the chance of getting a usable blastocyst and achieving pregnancy in IVF cycles with fragmented embryos.
What could go wrong: This is a relatively early-stage trial with no prior large-scale evidence. The procedure involves micromanipulation and laser use, which carries a small risk of embryo damage. Results may not apply to all fertility clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EMBRYO DEVELOPMENT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

female infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMBRYO DEVELOPMENT FEMALE INFERTILITY IN VITRO FERTILIZATION

Contacts and locations

Locations

MOMO' Fertilife
RECRUITING

Bisceglie, BT, 76011, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.