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New drug duo aims to deepen leukemia remission

NCT ID NCT07271667

Recruiting now Disease control Sponsor: Curis, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding emavusertib to a standard targeted therapy (zanubrutinib) can improve outcomes for people with chronic lymphocytic leukemia (CLL) and other B-cell cancers. About 108 adults with CLL who have already received some treatment will take both drugs. The goal is to see if the combination can make cancer undetectable or shrink tumors, but ongoing medication is expected.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

B-CELL MALIGNANCIES CHRONIC LYMPHOCYTIC LEUKEMIA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Azienda Ospedale Università Padova

    RECRUITING

    Padova, 35128, Italy

  • Azienda Ospedaliero Universitaria Maggiore Della Carità

    RECRUITING

    Novara, 28100, Italy

  • Hospital Universitario Fundación Jiménez Díaz - START MADRID

    RECRUITING

    Madrid, 28040, Spain

  • IRCCS Ospedale San Raffaele

    RECRUITING

    Milan, 20132, Italy

  • MD Anderson Cancer Center Madrid

    RECRUITING

    Madrid, 28033, Spain

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Mt Sinai Comprehensive Cancer Center

    RECRUITING

    Miami Beach, Florida, 33140, United States

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • Summit Medical Group

    RECRUITING

    Florham Park, New Jersey, 07932, United States

  • Texas Oncology - Sammons Cancer Center

    RECRUITING

    Dallas, Texas, 75246, United States

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.