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Experimental drug aims to help nerves regrow after spinal injury

NCT ID NCT04295538

Completed Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

Summary

This study tested whether a new drug called elezanumab could help improve arm and hand movement in people who had recently suffered a neck spinal cord injury. About 60 participants received either the drug or a placebo (inactive substance) starting within 24 hours of their injury and continuing for about a year. The main goal was to check the drug's safety and see if it could help nerves regrow and improve function.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ajou University Hospital /ID# 241119

    Suwon, Gyeonggido, 16499, South Korea

  • Beth Israel Deaconess Medical Center /ID# 218149

    Boston, Massachusetts, 02215-5400, United States

  • Brigham & Women's Hospital /ID# 216342

    Boston, Massachusetts, 02115, United States

  • CIUSSS du Nord-de-l'ile-de-Montréal_Hopital du Sacré-Coeur de Montréal /ID# 215210

    Montreal, Quebec, H4J 1C5, Canada

  • Complejo Hospitalario Universitario A Coruña /ID# 216384

    A Coruña, A Coruna, 15006, Spain

  • Duplicate_Boston University School of Medicine /ID# 218371

    Boston, Massachusetts, 02118-2515, United States

  • Duplicate_Duke Cancer Center /ID# 216888

    Durham, North Carolina, 27710-3000, United States

  • Duplicate_Inha University Hospital /ID# 238890

    Junggu, Incheon Gwang Yeogsi, 22332, South Korea

  • Duplicate_Tufts Medical Center /ID# 225410

    Boston, Massachusetts, 02111, United States

  • Foothills Medical Centre /ID# 214790

    Calgary, Alberta, T2N 2T9, Canada

  • Funabashi Municipal Medical Center /ID# 225599

    Funabashi-shi, Chiba, 273-8588, Japan

  • Hackensack Univ Med Ctr /ID# 215754

    Hackensack, New Jersey, 07601, United States

  • Hospital Nacional de Paraplejicos /ID# 225508

    Toledo, 45071, Spain

  • Hospital Universitario 12 de Octubre /ID# 225354

    Madrid, 28041, Spain

  • Hospital Universitario Vall de Hebron /ID# 217794

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen del Rocio /ID# 225692

    Seville, 41013, Spain

  • Hospital Universitario y Politecnico La Fe /ID# 217797

    Valencia, 46026, Spain

  • Japan Organization of Occupational Health and Safety Spinal Injuries Centre /ID# 224141

    Iizuka-shi, Fukuoka, 820-8508, Japan

  • Jersey Shore University Medical Center /ID# 218162

    Neptune City, New Jersey, 07753-4859, United States

  • NHO Nagoya Medical Center /ID# 239617

    Nagoya, Aichi-ken, 460-0001, Japan

  • National Hospital Organization Murayama Medical Center /ID# 223492

    Musashimurayama-shi, Tokyo, 2080011, Japan

  • Northwestern University Feinberg School of Medicine /ID# 218009

    Chicago, Illinois, 60611-2927, United States

  • Oregon Medical Research Center /ID# 227371

    Portland, Oregon, 97239, United States

  • QEII - Health Sciences Centre /ID# 215249

    Halifax, Nova Scotia, B3H 2Y9, Canada

  • Regents of the University of Michigan /ID# 215890

    Ann Arbor, Michigan, 48109-1276, United States

  • Royal Adelaide Hospital /ID# 216953

    Adelaide, South Australia, 5000, Australia

  • Rutgers New Jersey School of Medicine /ID# 216212

    Newark, New Jersey, 07103, United States

  • Sentara Norfolk General Hospital /ID# 218302

    Norfolk, Virginia, 23507, United States

  • Shepherd Center, Inc /ID# 230370

    Atlanta, Georgia, 30309-1426, United States

  • The Chaim Sheba Medical Center /ID# 240917

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Ottawa Hospital Civic Campus /ID# 215270

    Ottawa, Ontario, K1Y 4E9, Canada

  • Thomas Jefferson University Hospital /ID# 215460

    Philadelphia, Pennsylvania, 19107, United States

  • Toronto Western Hospital /ID# 215214

    Toronto, Ontario, M5T 2S8, Canada

  • University of California Davis Health /ID# 224892

    Sacramento, California, 95817, United States

  • University of Louisville Hospital /ID# 215948

    Louisville, Kentucky, 40202, United States

  • University of Pennsylvania /ID# 218662

    Philadelphia, Pennsylvania, 19104-5502, United States

  • University of Virginia Health /ID# 218117

    Charlottesville, Virginia, 22908, United States

  • Virginia Commonwealth University Medical Center Main Hospital /ID# 217481

    Richmond, Virginia, 23219, United States

  • Washington University-School of Medicine /ID# 215325

    St Louis, Missouri, 63110, United States

  • West Virginia University Hospitals /ID# 217344

    Morgantown, West Virginia, 26506, United States

  • Wisconsin Medical Center /ID# 215610

    Milwaukee, Wisconsin, 53226, United States

Conditions

Explore the condition pages connected to this study.

SPINAL CORD INJURY (SCI)