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Implanted nerve stimulator aims to restore walking after spinal injury

NCT ID NCT07689227

Not yet recruiting Disease control Sponsor: The University of Texas at Dallas Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tests a device called the ReWire system, which is implanted to stimulate the vagus nerve during leg rehabilitation. The goal is to see if this paired stimulation can safely improve walking in people with chronic, incomplete spinal cord injury. The trial involves 20 participants who will receive either active stimulation or a sham (inactive) treatment during rehab sessions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ReWire system (implanted vagus nerve stimulator)
What this could lead to
If it works, this could offer a new way to improve walking ability in people with chronic spinal cord injury.
What could go wrong
This is an early feasibility study with only 20 participants, so results may not apply broadly. The device requires surgery, which carries risks like infection or device-related complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gait apraxia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FUNCTIONAL MOBILITY GAIT LOWER LIMB FUNCTIONS MOBILITY IMPAIRMENT REDUCED PHYSICAL ACTIVITY SPINAL CORD INJURY(SCI) WALKING IMPAIRMENT

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor University Medical Center (BUMC)

    Dallas, Texas, 75246, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Spaulding Rehabilitation Hospital, Mass General Brigham

    Boston, Massachusetts, 02129, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Biomedical Device Center

    Richardson, Texas, 75080, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Urgent Surgery Associates, PA

    Dallas, Texas, 75204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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