Diabetes drug metformin could help heal spinal cord injuries

NCT ID NCT07272967

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether metformin, a common diabetes medicine, can help people recover after a spinal cord injury. The drug may reduce scar tissue that blocks nerve healing. Researchers will give metformin or a placebo to 34 adults with recent thoraco-lumbar spinal cord injury and measure their neurological recovery and pain levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Metformin (Glucophage) 1000 mg tablets

What this could lead to

If it works, this could point toward a new, safe way to improve nerve recovery and reduce pain after spinal cord injury.

What could go wrong

This is a small early-phase trial with only 34 participants, so results may not apply widely. Metformin's effect on spinal cord injury is still unproven in humans.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Gliosis spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Neurosurgery department at Menoufia University hospitals at Menoufia University.

    Shibīn al Kawm, Menoufia, 32817, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••