Can the right electric pulse calm chronic worry?
NCT ID NCT07798986
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
This trial tests whether different electroacupuncture frequencies can ease symptoms of generalized anxiety disorder, a condition marked by persistent, excessive worry. Researchers will compare three stimulation patterns (2 Hz, 100 Hz, and a mixed 2/100 Hz wave) against a sham version in 120 adults aged 18 to 60. Each participant receives 12 sessions over four weeks, and the team measures anxiety using standard rating scales. The goal is to find out which setting, if any, provides the most relief.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Electroacupuncture at different frequencies (2 Hz, 100 Hz, and 2/100 Hz dense-disperse wave) compared with sham electroacupuncture
- What this could lead to
- If it works, this could identify the most effective electroacupuncture settings for easing anxiety, offering a drug-free option for people with generalized anxiety disorder.
- What could go wrong
- The trial is relatively small and early, and it compares different versions of the same treatment, so any difference between them may be modest. Results depend on how well participants respond, and electroacupuncture may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Only those who meet the following four criteria simultaneously can be included in this study: 1. Meet the diagnostic criteria for GAD; 2. Between 18 and 60 years old; 3. Conscious and able to communicate normally; 4. Have good compliance, be willing to cooperate with the study, and sign the informed consent form. Exclusion Criteria: Exclude patients meeting any of the following criteria: 1. Organic mental disorder, schizophrenia, bipolar disorder, mania/other psychoses, alcohol/drug addiction, current drug use disorder/lifetime drug abuse, post-stroke/postpartum anxiety; 2. History of suicidal behavior or severe suicidal tendency; 3. Pregnancy or breastfeeding; 4. Mental retardation, unable to cooperate; 5. Electroacupuncture contraindications: bleeding tendency, coagulation dysfunction, internal metal implants; 6. Participation in other clinical trials within 1 month.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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2nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang, China
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Other studies related to the condition(s) this trial covers.
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- Can online therapy or parent coaching ease childhood anxiety? a head-to-head trial aims to find out.
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