New hope for elderly lymphoma patients: a gentler treatment that preserves independence
NCT ID NCT04113226
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial investigates whether combining rituximab with lenalidomide works as well as standard rituximab-based chemotherapy for patients aged 75 and older with relapsed diffuse large B-cell lymphoma. The study focuses not only on controlling the cancer but also on maintaining the patients' ability to perform daily activities independently. Participants receive either the lenalidomide combination or standard chemotherapy, with the goal of finding a treatment that balances effectiveness with quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rituximab and Lenalidomide
- What this could lead to
- If successful, this could offer a gentler, effective treatment option for elderly patients with relapsed DLBCL, helping them live longer while maintaining independence.
- What could go wrong
- This is a small, early-phase trial, so results may not apply broadly. Lenalidomide can cause side effects like low blood counts, fatigue, or blood clots.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens
Amiens, 80054, France
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