Could blood pressure drugs slow Parkinson's? major trial launches

NCT ID NCT07207057

First seen Nov 01, 2025

Summary

This large Phase 3 trial is testing whether two common drugs, telmisartan and terazosin, can slow the progression of Parkinson's disease. 1,200 participants will receive either a drug or a placebo for up to 36 months. The study uses a flexible design that can add new treatments over time, aiming to find effective therapies faster.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PARKINSONS DISEASE (PD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Ageing Research Unit

    RECRUITING

    Newcastle, NE4 5PL, United Kingdom

  • UCLH

    RECRUITING

    London, NW1 2PG, United Kingdom

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Telmisartan and terazosin (drugs repurposed for Parkinson's disease)

What this could lead to

If successful, this could provide new, safe treatments that slow the progression of Parkinson's disease, helping people maintain their abilities longer.

What could go wrong

This is an early-stage platform trial; the drugs may not slow progression. Side effects from the medications are possible, and results may take years to confirm.

Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.