Scientists hunt for fingerprints of a genetic form of Parkinson's

NCT ID NCT07681219

Not yet recruiting Knowledge-focused Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study aims to find unique biological and clinical markers for a specific genetic form of Parkinson's disease linked to the LRRK2 gene. Researchers will compare 10 people with LRRK2-related Parkinson's to 10 people with sporadic Parkinson's using blood tests, brain MRI scans, and high-density EEG. The goal is to better understand how this form of the disease differs, which could improve diagnosis and guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors identify and track LRRK2-related Parkinson's disease more precisely, potentially leading to earlier diagnosis or targeted treatments.
What could go wrong: This is a small, early-stage study with only 20 participants, so findings may not apply to all people with Parkinson's. It is designed to gather information, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LRRK2 PARKINSONS DISEASE (PD)

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Other studies related to the condition(s) this trial covers.