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Precision brain stimulation: which target best stops Parkinson's tremor?

NCT ID NCT07700862

Recruiting now Disease control Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether directional deep brain stimulation (DBS) works better when aimed at the posterior subthalamic area (PSA) or the subthalamic nucleus (STN) for controlling tremor in people with tremor-dominant Parkinson's disease. Each participant will receive stimulation in both targets at different times to compare tremor control. The study uses a directional lead to focus the electrical pulses more precisely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
directional deep brain stimulation
What this could lead to
If successful, this could identify the best brain target for directional DBS to better control tremor in Parkinson's disease.
What could go wrong
This is a small, early-stage trial with only 32 participants, so results may not apply to everyone. The procedure carries surgical risks and stimulation side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSONS DISEASE (PD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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