Could a longer ER stay help more people start opioid addiction treatment?

NCT ID NCT05064826

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares standard emergency department care to an extended observation period for people with opioid use disorder. Participants are randomly assigned to either leave after a regular ED visit or stay longer in an observation unit to receive their first dose of buprenorphine and get a warm handoff to follow-up care. The goal is to see if the extended approach increases the number of people who start medication and stay engaged in treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

buprenorphine (BUP)

What this could lead to

If successful, this could show that keeping people in the ED for observation helps them start addiction medication and connect to follow-up care more reliably.

What could go wrong

This is a mid-stage trial with 170 participants, so results may not apply to all settings. The main focus is on starting treatment, not long-term outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bellevue

    New York, New York, 10016, United States

  • NYULH-Brooklyn

    Brooklyn, New York, 11220, United States

  • NYULH-Tisch

    New York, New York, 10016, United States

  • Northwell Health - Long Island Jewish Medical Center

    New Hyde Park, New York, 11040, United States

  • Northwell Health - Staten Island University Hospital

    Staten Island, New York, 10305, United States

  • Rutgers University-University Hospital

    Newark, New Jersey, 07103, United States