Race against time: two powerful treatments battle suicidal depression in major study
NCT ID NCT06034821
First seen Nov 01, 2025 · Last updated Apr 20, 2026 · Updated 24 times
Summary
This large study compares two fast-acting treatments—electroconvulsive therapy (ECT) and ketamine—for people experiencing severe depression with suicidal thoughts. Researchers want to see which treatment works better at quickly reducing suicidal thinking in 1,500 adults aged 18-90. The goal is to help people achieve full remission from suicidal thoughts, which is critical since this condition is life-threatening.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Center for Addiction and Mental Health (University of Toronto)
Toronto, Ontario, M6J 1H4, Canada
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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McLean Hospital
Belmont, Massachusetts, 02478, United States
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Mount Sinai School of Medicine
New York, New York, 10029, United States
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UC San Francisco
San Francisco, California, 94143, United States
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UTHealth Houston
Houston, Texas, 77030, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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University of Utah
Salt Lake City, Utah, 84132, United States
Conditions
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