Vital signs alert could save lives in blood cancer care

NCT ID NCT06409767

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether using a simple early warning score (NEWS) to quickly move high-risk blood cancer patients to the ICU can reduce deaths and organ failure. Over 2,200 adults receiving intensive chemotherapy or stem cell transplants will take part across ten hospitals. Half the hospitals will use the warning system; the other half will continue usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
National Early Warning Score (NEWS) monitoring with ICU referral
What this could lead to
If it works, this could show that closely monitoring vital signs and acting early saves more lives in blood cancer patients undergoing intensive treatment.
What could go wrong
This is a large trial but it tests a monitoring strategy, not a new drug. The benefit may be small, and early ICU admission could increase anxiety and resource use without improving survival.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Amiens-Picardie

    RECRUITING

    Amiens, 80054, France

  • Centre Hospitalier Universitaire Besancon

    RECRUITING

    Besançon, 25030, France

  • Centre Hospitalier Universitaire Brest

    RECRUITING

    Brest, 29609, France

  • Centre Hospitalier Universitaire Nantes

    RECRUITING

    Nantes, 44093, France

  • Centre Hospitalier Universitaire d'Angers

    RECRUITING

    Angers, 49933, France

  • Centre Hospitalier Universitaire poitiers

    RECRUITING

    Poitiers, 86021, France

  • Centre Hospitalier universitaire Nancy

    RECRUITING

    Nancy, 45011, France

  • centre Hospitalier Universitaire Saint etienne

    RECRUITING

    Saint-Etienne, 42270, France

  • centre Hospitalier Universitaire Strasbourg

    NOT_YET_RECRUITING

    Strasbourg, 67098, France

  • centre Hospitalier Universitaire Tours

    RECRUITING

    Tours, 37044, France

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